CRISPR Conference, 3D Printing, and Star Wars

January 5, 2016
Description: In this podcast we talk about the use of CRISPR to engineer humans. Is it ethical? Should we do it if it helps humans? We also discuss the use of 3D printers in the medical field, as well as the colonization of Mars. Are you a Star Wars fan? We have a fun conversation about the new Star Wars movie coming out this week. Click through to listen!

Another Obesity Drug Trial Death
Let's Talk Human Engineering
3D-Printed Body Parts Help Surgeons Separate Conjoined Twins
Combating Whooping Cough
Scientists Create 3D Printed Blood Vessels Using 'Bio-Ink'

Keywords: CRISPR, genes, gene editing, humans, bioethics, Mars, colonization, 3D printers, surgery, conjoined twins, Star Wars, designer babies, science, podcast, photosynthesis


Blood Brain Barrier, Meningitis, and Sense of Humor

November 20, 2015
Description: In this episode, the podcast team gets together once again to talk about some newsworthy science stories! Here, we discuss how ultrasounds have helped us breach the blood-brain-barrier, and how subtle changes to the things someone finds funny may be an early sign of dementia. We also talk about how being lazy may be explained neurologically, "supernatural" killer cells, and lab kits, now on crowdfunding platforms, that let you do your own genome editing at home. Give it a listen!

Breaching the Blood-Brain-Barrier
A Dark Sense of Humor May Be a Sign of Dementia
Editing DNA in Your Own Home
A Cheap Vaccine Is Wiping Out Meningitis A in Africa
Engineering Super Natural Killer Cells
A Neurological Basis of Apathy
3D Printed Objects as Implants

Keywords: neuroscience, dementia, neurodegeneration, blood-brain-barrier, BBB, ultrasound, Parkinson's disease, DNA, CRISPR, lab kit, crowdfunding, Meningitis, Africa, vaccines, Super Natural Killer Cells, NK Cells, apathy, laziness, 3D printing, dental implants


Smelling Parkinson’s, Special Antibodies in HIV and Cancer, and a Cloud of Microbes

November 9, 2015
Description: In this episode, we discuss some a variety of current scientific news, including the discovery of woman who can smell Parkinson's disease, a correlation between bovine leukemia virus and breast cancer, using an individual's microbial cloud to identify them, and how we're using specialized antibodies to combat both HIV and cancer.

Woman in able to smell Parkinson's disease
Unique microbe clouds surround individuals
Missing gut bacteria associated with higher asthma risk
Reprogramming leukemia cells to kill each other
BLV proteins associated with breast cancer
Activating and killing latent HIV in infected cells
Watch the 360° Podcast Video
Download video for VR

Keywords: neuroscience, neurodegeneration, Parkinson's disease, microbes, microbial, gut microbiome, bacteria, asthma, allergy, leukemia, cancer, AML, antibody, virus, cow, bovine, breast cancer, HIV, AIDS


Nobel Prizes, CRISPR 2.0, and Lazy Ants

October 26, 2015
Description: In this podcast episode, also recorded in 360 video, the team discusses the contributions of the recent Nobel Prize winners in Chemistry and Physiology/Medicine, a new CRISPR, and lazy slacker ants.

Nobel Prize winners
A new and improved CRISPR?
Majority of ant workers are slackers
Watch the 360° Podcast Video
Download video for VR

Keywords: Nobel Prize, YouYou Tu, Artemisinin, malaria, Thomas Lindahl, Paul Modrich, Aziz Sancar, DNA repair, base excision repair, nucleotide excision repair, cancer, mutations, CRISPR, Feng Zhang, Cas9, Cpf1, ants, colonies


Vitamin C, Theranos and Pain

October 12, 2015
Description: Team Podcast gets together in this episode to discuss recent findings about vitamin C and its usage in our society, a recently discovered gene variant that is associated with delayed early-onset Alzheimer's, how sugar is sugar (no matter how "natural" it is), and an amazing young entrepreneur, Elizabeth Holmes, the founder of Theranos.

Gene Variant Provides Delaying Mechanism in Alzheimer's Disease
Vitamin C Mimics Some Effects of Exercise
Honey, Sugar, and Corn Syrup Have Similar Metabolic Effects
Elizabeth Holmes, Founder of Theranos

Keywords: neuroscience, Alzheimer's disease, neurodegeneration, eotaxin, vitamin C, ascorbic acid, overweight, weight loss, metabolism, cardiovascular disease, diabetes, glucose, sucrose, sugar, honey, HFCS, corn syrup, high fructose, cholesterol, blood pressure, Elizabeth Holmes, Theranos, billionaire, entrepreneur, lab-on-a-chip


Global Health Science with Jessica Taaffe

September 23, 2015
Description: Special guest and global health scientist Jessica Taaffe joins us to discuss educating the public, funding research, and the passion needed in scientific role models.

Jessica Taaffe's Homepage
This Week in Global Health
Holding Out For a [Scientific] Hero
Follow Jessica and BioLegend on twitter: @jessicataaffe, @biolegend

Keywords: global health, Jessica Taaffe, HIV, ebola, education, Bill Nye, Neil degrasse Tyson, vaccines, anti-vaxxers, world bank, funding, research, NIH, primates, BioLegend, podcast


Salmonella and Plague Outbreaks

September 16, 2015
Description: In this episode, the podcast team discusses Salmonella and plague outbreaks, HIV transmission, and glow in the dark GMO chickens resistant to bird flu.

Salmonella Outbreak Spreading Across America Is Linked To Cucumbers
Plague Outbreak in Madagascar
Immune Cells Can Deliver Deadly Packages
Glowing in the dark, GMO chickens shed light on bird flu fight

Keywords: salmonella, plague, pneumonic plague, bubonic plague, yersinia pestis, HIV, AIDS, quarantine, exosomes, chickens, avian flu, bird flu


Venom and Ancient Viruses

September 15, 2015
Description: The podcast team discusses the potential anti-venom shortage, a wasp-venom derived protein for cancer therapy, 30,000 year-old viruses, and a new hominid species discovered in South Africa.

Snakebite Anti-Venom Set To Run Out Next Year
Scientists Plan On Resurrecting A 30,000-Year-Old Giant Virus
Brazilian Wasp Venom Kills Cancer Cells, But Not Healthy Cells
New Homo Species Found
Watch The Fight Between A Mongoose And A Cobra

Keywords: venom, anti-venom, snakebites, wasp venom, Fav-Afrique, MP1, Polybia-MP1, Polybia paulista, phosphatidylserine, annexin V, cancer cells, homo naledi, fossils, Mollivirus sibericum, viruses, Siberia, giant viruses


Polio, Legionnaires’, and Leptin

September 10, 2015

On this podcast, we discuss current events in science, including recent outbreaks of polio in the Ukraine and Legionnaire’s disease in California and Illinois. We also cover recent research linking high-fat diets with a change in the gut microbiome and obesity-linked inflammation, as well as the role that leptin plays in the rewarding effects of exercise. Tune in to hear our discussion on the release of an open-access journal that will publish ideas as well as data and results, and other exciting research on influenza infection.

Keywords: polio, Legionnaire’s disease, outbreaks, virus, bacteria, saturated fats, obesity, microbiome, mice, inflammation, leptin, neurons, brain, exercise, neutrophils, T cells, infection, lungs, influenza, open-access, journal, the wall of polio, science, podcast, virology, immunology


Legionnaires' Outbreak Contained At Calif. Prison; New Cases In Illinois
A new journal wants to publish your research ideas
How Fats Influence the Microbiome
Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling
Leptin Suppresses the Rewarding Effects of Running via STAT3 Signaling in Dopamine Neurons
Neutrophil trails guide influenza-specific CD8+ T cells in the airways
The Wall of Polio


Brain Tumors with Mohar Chattopadhyay

August 31, 2015

Glioblastomas and medulloblastomas are two common forms of brain cancer that afflicts thousands of people a year. Tune in to hear our guest Mohar Chattopadhyay discuss its symptoms, treatments, and research.
Keywords: glioblastoma, medulloblastoma, biolegend, science, neuroscience, podcast, cancer, brain, cerebellum, p53, PI3K, MAPK, RB, genetics, symptoms, diagnosis, glial cells, microglia


Brain cancer/cell phone usage comparison
Epidemiology and molecular pathology of glioma
Current trends in targeted therapies for glioblastoma multiforme
Biological background of pediatric medulloblastoma and ependymoma: a review from a translational research perspective