Note regarding our talk on the polio vaccine: Following its mass production in 1955, certain pharmaceutical companies failed to properly inactivate the Salk vaccine, leading to over 250 reported cases of paralysis. Salk’s inactivated polio vaccine was the first developed, followed by the oral polio vaccine (OPV). OPV remained in use in the US until 1999 where it was replaced with an inactivated, injectable vaccine. However, OPV is still used in other countries around the world.

Topics

Common vaccination myths
WHO's ten threats to global health in 2019
Teen secretly gets vaccinated, speaks to Senate
Unvaccinated teen sues school for limiting his activity
Facebook to ban anti-vaxx ads in new push against 'vaccine hoaxes'
Measles returns to Costa Rica thanks to unvaccinated family
Anti-Vaxx mom asks how she can protect her 3 year old from Measles outbreak
Study on 657,461 children finds no link between autism and vaccines

Keywords: vaccines, measles, immunology, anti-vaxxers, autism, Andrew Wakefield, myths, science, Ethan Lindenberger, kale, global health, chickenpox

Topics

The Controversy Over HeLa Cells
The Henrietta Lacks Foundation
The Legacy of Henrietta Lacks (Johns Hopkins Medicine)
Johns Hopkins to name research building after Henrietta Lacks
Moore v. Regents of the University of California
Dat Tran and Lick-A-Bubble
Harry Potter Spoilers (15:32-15:50)

Keywords: Henrietta Lacks, podcast, HeLa cells, cell line, telomeres, telomerase, polio, senescence, Helen Lane, cancer, Johns Hopkins, George Otto Gey, The Immortal Life of Henrietta Lacks, Rebecca Skloot, John Moore, David Golde

Topics

Microtunnels in the Skull (2:11-10:04)
Russia Is Opening A "Jurassic Park-Style" Research Lab (10:05-19:45)
The Fantasy Scientist Draft (22:05-26:25)
Gut Bacteria, Bullying, Junk Food, and You! (26:26-42:20)
God of War Shout-out (46:52)
Successful Placebo Pills (47:48-52:20)

Keywords: Immunology, podcast, brain, skull, marrow, microtunnels, extinction, Jurassic park, dodo, wooly mammoth, dna, fantasy football, microbiota, gut bacteria, memory, bullying, junk food, diet, psychobiotics, elderberries, Placebo Effect, honest placebo, IBD, inflammatory bowel disease

Topics

Epstein-Barr Virus and Autoimmunity (2:20-12:00)
Nipah Virus Outbreaks (12:01-20:35)
Bacteria Coats itself with IgA for Protection (23:23-32:23)
Out of Whack Fetal Immune Systems Prompt Preterm Labor (35:45-43:33)

Keywords: autoimmunity, kissing disease, mononucleosis, Nipah Virus, herpes, Epstein-barr virus, cancer, bats, reservoir, Bacteroides fragilis, IgA, gut, mucosa, bacteria, pregnancy, premature birth, fetal immunity, preterm

Topics

Final Fantasy VII (Podcast from 2:35-14:20)
Resident Evil (Podcast from 14:20-26:50)
The Last of Us (Podcast from 31:50 to 44:00; Spoilers from 41:20 to 42:18)
Viruses in the Resident Evil Series
The Last of Us Part II
Stages of Infection in the Last of Us
Cordyceps: Attack of the Killer Fungi-Planet Earth with David Attenborough

Intro music “The Pirate and the Dancer” by artist Rolemusic at the Free Music Archive.

Keywords: video games, science, podcast, resident evil, final fantasy VII, Jenova, CRISPR, gene splicing, Sephiroth, virus, T-virus, mitochondria, retrovirus, reverse transcriptase, Ebola, Atari, playstation, The Last of Us, Cordyceps, fungus

Topics

The Undersea LEGENDplex™ Adventure
LEGENDplex™ Plush Plexy Promotion
New human antibody prevents malaria in mice
Class time affects grades
School starts too early according to CDC

Keywords: malaria, Jason Lehmann, mosquito, parasite, infectious disease, plasmodium falciparum, vivax, Haiti, cytokines, multiplexing, LEGENDplex, CIS43, social jetlag, Beatles, octopus

Topics

In remembrance of Stephen Hawking
SEC press release on Theranos and Elizabeth Holmes
Could Rapamycin help humans live longer?
High-Fiber Diet Shifts Gut Microbes, Lowering Blood Sugar in Diabetics
Personal cancer vaccines show promise

Keywords: Stephen Hawking, A Brief History of Time, ALS, Amyotrophic Lateral Sclerosis, Theranos, Elizabeth Holmes, rapaymycin, microbiome, fiber, gut bacteria, type 2 diabetes, cancer vaccine

The thoughts and opinions of our guest, Jonathan Deane, are his own personal reflections and do not necessarily reflect the opinions or positions of The Genomics Institute of the Novartis Research Foundation (GNF).

Topics

The Genomics Institute of the Novartis Research Foundation
Jonathan Deane’s TLR7 article and painting
The American Association of Immunologists Advocacy Center
The Good and Bad of Generic Drugs
Pricing Pharmaceuticals, Parts 1 and 2
Giving a Scientific Talk, Parts 1 and 2

Keywords: Jonathan Deane, drug discovery, podcast, BioLegend, GNF, genomics institute of the Novartis research foundation, pharmaceutical, toastmasters, innate immunity, TLR7, clinical, American Association of Immunologists, lupus

Topics

Emerging Technologies in BioTech Podcast with John Ransom
GMOs, Organic Food and Science Myths Podcast with Lauren Uhde, the Biology Babe
Global Health Science Podcast with Jessica Taaffe
The Post-Doc Experience Podcast with Francesca Soncin
Interview with William Golde on T Suppressor Cells

Keywords: podcast, anniversary, T suppressor cells, Tregs, grad students, post-docs

Topics

CRISPR may be ineffective in human trials due to immunity
First US CRISPR trials will target cancer
Why this year’s flu season is so much worse in the US, UK and Australia
How are subtypes of the flu named?
Is the man-flu real?
Man ruptures throat after holding in sneeze
Fast food may make your immune system more aggressive
High salt diet produces dementia in mice

Keywords: influenza, H3N2, CRISPR, fast food, salt, vaccines, man flu, Cas9, immunity, BioLegend, podcast, immunology, diet